By PD Dr. med. Ulrich F. Gruber (auth.)
The manifold difficulties of outrage are nonetheless of serious value, diagnostic and healing adventure of the "severely unwell" being provided with new details virtually each month. within the five periodicals that have came across their strategy to my table up to now few days there are not any under 10 attention-grabbing articles on questions relating surprise study [see Bibliography forty-one b, fifty three a, 60 a, 192 a, 242 a, 350 b, 810 a, 941 a, 1069 a, 1082 a]. the main pressing element nonetheless is to keep up as entire as attainable the target catalog of a number of the surprise manifestations present in guy and in animals - but even as to view interpretations of those phenomena of their relative and temporal "truth". difficulties of outrage examine aren't simply fascinating for his or her clinical worth but additionally for his or her scientific implication. specifically, virtually each training health professional is dealing with difficulties of blood substitute very widespread ly. The potent or circulating blood quantity continues to be a major theoret ical and healing challenge within the surprise box. For years, U. F. GRUBER has pursued this question clinically and experimentally. This quantity bargains with the area literature in an extremely thorough demeanour. This booklet is made greater than a compilation via together with a protracted checklist of unique paintings performed with F. D. MOORE in Boston, within the Surgical division in Chur, with 1. E. GELIN and S. E.
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Extra info for Blood Replacement
5010 . In general a half-life of approx. 34 days is assumed for transfusec erythrocytes [245, 621] (see also point 4, p. 26). Table 2. Changes in citrated blood during storage at 4 ± 1° C (ace. STRUMIA ) Days a 7 14 21 28 Hemoglobin mg-Ofo pH Glucose mg-% Lactic aCid mg-% Inorganic phosphate mg-Ofo Sodium mval/l Potassium mvalfl Ammonia /lg_% 0-10 7,00 350 20 1,8 150 3-4 50 25 6,85 300 70 4,5 148 12 260 50 6,77 245 120 6,6 145 24 470 100 6,68 210 140 9,0 142 32 680 151 6,6 19 15 9, 14 4 A similar table is found in ALBERT .
The results of our measurements can be seen in Figs. 2, 3, 4 and 5. 3 persons out of 9 who received homologous plasma showed allergic reactions: one with chills, two with temporary urticarial symptoms, a serious urticaria occurring in one of the volunteers who at the same time showed a massive plasma loss. Significant changes in pulse, blood pressure and temperature could not be determined (for detailed results see GRUBER ). SV3 Blood volu m e normal + -~~-~:~-----------......... -.... - ..................
Similar preparations: 1. Albumin human SOlo and 20010, Immuno GmbH, Heidelberg/Vienna, 2. Humanalbumin "Behringwerke" 50/0 and 20 0/0, 44 Various Methods of Volume Replacement 3. Humanalbumin "Biotest" 50 /0 and 20010, 4. Albumin (normal serum albumin, human) 25010, 50 ml. w. or of another colloid (dextran 40) in dogs strongly increases the bleeding time. This is a non-specific effect due to circulatory overloading. II. The Volume Effect of Plasma 1. Fresh Plasma Fresh plasma, in all its properties, corresponds to the plasma portion of ordinary citrated blood (compare ).
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