Bioinformatics: A Practical Guide to the Analysis of Genes by Andreas D. Baxevanis, B. F. Francis Ouellette

By Andreas D. Baxevanis, B. F. Francis Ouellette

"In this booklet, Andy Baxevanis and Francis Ouellette . . . have undertaken the tricky activity of organizing the data during this box in a logical development and offering it in a digestible shape. and so they have performed a very good task. This tremendous textual content will make an incredible influence on organic study and, in flip, on development in biomedicine. we're all of their debt."
—Eric Lander from the Foreword
Reviews from the 1st Edition
"...provides a large assessment of the elemental instruments for series research ... For biologists forthcoming this topic for the 1st time, it is going to be a really invaluable guide to maintain at the shelf after the 1st analyzing, with reference to the computer."
Nature Structural Biology
"...should be within the own library of any biologist who makes use of the web for the research of DNA and protein series data."
Science
"...a outstanding primer designed to navigate the amateur throughout the intricacies of in scripto research ... The complete gene searcher also will locate this e-book an invaluable addition to their library ... a superb connection with the foundations of bioinformatics."
Trends in Biochemical Sciences
This new version of the hugely winning Bioinformatics: a pragmatic advisor to the research of Genes and Proteins offers a valid starting place of uncomplicated recommendations, with sensible discussions and comparisons of either computational instruments and databases proper to organic research.
Equipping biologists with the fashionable instruments essential to resolve useful difficulties in series info research, the second one variation covers the vast spectrum of issues in bioinformatics, starting from net suggestions to predictive algorithms used on series, constitution, and expression information. With chapters written via specialists within the box, this up to date reference completely covers important techniques and is acceptable for either the amateur and the skilled practitioner. Written in transparent, basic language, the publication is obtainable to clients with out a complicated mathematical or machine technological know-how heritage. This new version includes:* All new end-of-chapter net assets, bibliographies, and challenge units* Accompanying site containing the solutions to the issues, in addition to hyperlinks to suitable internet assets* New insurance of comparative genomics, large-scale genome research, series meeting, and expressed series tags* A word list of time-honored phrases in bioinformatics and genomics
Bioinformatics: a realistic consultant to the research of Genes and Proteins, moment version is key studying for researchers, teachers, and scholars of all degrees in molecular biology and bioinformatics, in addition to for investigators enthusiastic about genomics, positional cloning, scientific examine, and computational biology.

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Extra info for Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins (2nd Edition)

Example text

Each sequence will eventually get an accession. version identifier and a gi number, but only when the completed submission has been processed by one of the public databases. During the submission process, Sequin assigns a local identifier to each sequence. Because many of the software tools made by NCBI require a sequence identifier, having a local Seq-id allows the use of these tools without having to first submit data to a public database. BIOSEQs: SEQUENCES The Bioseq, or biological sequence, is a central element in the NCBI data model.

The information retrieved from the remote host is in a platform-independent format named hypertext markup language (HTML). HTML code is strictly text-based, and any associated graphics or sounds for that document exist as separate files in a common format. For example, images may be stored and transferred in GIF format, a proprietary format developed by CompuServe for the quick and efficient transfer of graphics; other formats, such as JPEG and BMP, may also be used. Because of this, a browser can display any Web page on any type of computer, whether it be a Macintosh, IBM compatible, or UNIX machine.

In some cases, data submission precedes article publication by a considerable period of time, or a publication regarding a particular sequence may never appear in press. Because of this, there is a separate citation designed for deposited sequence data. The submission citation, because it is indeed an act of publication, may have an author list, showing the names of scientists who worked on the record. This may or may not be the same as the author list on a subsequently published paper also cited in the same record.

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Bioinformatics: A Practical Guide to the Analysis of Genes by Andreas D. Baxevanis, B. F. Francis Ouellette
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